Shailesh Vara resigns over Brexit draft deal disagreement

At the same time as ministers and Number 10 staffers were deserting her, Theresa May had endure a painful Commons debate in which both sides pronounced that her deal was dead.

On Wednesday night, she confirmed that "the collective decision of Cabinet was that the government should agree the draft withdrawal agreement and the outline political declaration".

"And if you can not do that, I respectfully ask you to do the right thing in the national interest and stand down to allow someone from the Brexit camp to take the lead".

Media captionBBC's Laura Kuenssberg asks the PM if she "in office, but not really in power?"

"This deal, which delivers on the vote of the referendum, which brings us back control of our money, laws and borders, ends free movement, protects jobs, security and our union, or leave with no deal, or no Brexit at all", she said.

Asked whether she was a modern-day Chamberlain, May told LBC radio: 'No I don't and the reason is this: we are not going to be locked in forever to something that we don't want'.

She said: "No. A lot of people look at this and think the only side that has given anything is the UK".

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Yesterday, Jacob Rees-Mogg publicly handed his letter of no confidence to Sir Graham Brady, chairman of the backbench 1922 Committee responsible for Tory leadership elections.

Speaking outside the House of Commons, he declined to run for leadership himself - but named Boris Johnson, David Davis, Dominic Raab and Esther McVey and Penny Mordaunt as candidates for PM.

Prime Minister Theresa May has reiterated that her deal is the best deal for the United Kingdom.

"Given the past performance of the EU, there is every possibility that the UK-EU trade deal that we seek will take years to conclude", he wrote.

The PM said: 'This is an issue that I feel personally - as it happens my insulin is produced by a company in the EU, Denmark, so I know this is an issue that's a matter of importance to people. But I believe we've got a good deal'.

Rumours are circulating that Environment Secretary Michael Gove is considering whether or not to follow him out of Government.

It is suggested as many as a third of the 28 ministers that attended that Cabinet meeting voiced doubts about the deal.

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