Alcohol Consumption Increases Cancer Risks, Damages DNA

Pouring alcohol in shot glasses

It also showed how the body seeks to defend against the damage alcohol can do."Some cancers develop due to DNA damage in stem cells".

Scientists have found clues as to why drinking alcohol increase a person's cancer risk, according to a study published last week in the scientific journal Nature.

They found that the chemical gave rise to permanent mutations in the mice's DNA sequences which could lead to various forms of cancers.

Researchers at the United Kingdom -based Medical Research Council Laboratory of Molecular Biology found that alcohol abuse can cause permanent damage to the DNA in the stem cells in charge of blood production.

Malcolm Alison, Professor of Stem Cell Biology at the Barts Cancer Institute, Queen Mary University of London, added: "Drinkers beware: most of our organs and tissues have stem cells, immortal cells that replenish cells lost through the likes of old age throughout our lives". Then they studied the genetic damage, using chromosomal analysis and DNA sequencing, caused by acetaldehyde, a harmful chemical released when the body processes the alcohol.

The effects of such damage can be neutralized, however, by the body's two-layer defense mechanism.

"While some damage occurs by chance, our findings suggest that drinking alcohol can increase the risk of this damage", said lead author Ketan Patel of the MRC Laboratory of Molecular Biology in Cambridge.

CES 2018: Lenovo unveils ThinkPad X1 Tablet, X1 Carbon, X1 Yoga
The Lenovo ThinkPad X1 Yoga features the same set of internals as found inside its robust and costlier brother, the X1 Carbon . The devices also come with Amazon Alexa on board with far-field microphones for interacting with the assistant.

Android Oreo Fails To Reach Even 1% Share
A further breakdown reveals that Android 8.0 takes a 0.5 percent share and the latest Oreo 8.1 sits at just 0.2 percent. If Android Nougat continues the same trend, we can see it closing onto Android Marshmallow in the next few months.

Bella Thorne opens up about suffering sexual abuse as a kid
She responded by revealing that while she had been a victim of abuse, it had nothing to do with the network. "All damn night. No to me taking a shower with him". "Little did I know it would become my turn to say no", she wrote.

The link between alcohol and certain types of cancer has been known for some time, but exactly how drinking can raise cancer risk has been less clear.

The research team also found that some people are more prone to alcohol-related DNA damage than other people.

Health watchdogs have long warned that alcohol consumption contributes to seven types of cancer - of the mouth, throat, larynx or voice box, oesophagus or food pipe, breast, liver and bowel. The body usually reacts to too much acetaldehyde by trying to break it down into energy.

"I$3 t's important to remember that alcohol clearance and DNA fix systems are not flawless and alcohol can still cause cancer in different ways, even in people whose defence mechanisms are intact". They learned that a byproduct of alcohol metabolism dubbed acetaldehyde turns into poison which can dramatically affect the drinker's DNA.

The researchers gave ethanol to mice lacking ALDH2, and discovered that these mice had four times as much damage in their DNA cells when compared with mice that had the enzyme.

The research was funded by Cancer Research UK, Wellcome and the Medical Research Council.

Related News:

  • Kanye West rapped on the phone for dying young fan

    Kanye West rapped on the phone for dying young fan

    Last May a young man named Tyler Wesley marked the five-year anniversary of his spinal cord injury that left him in a wheelchair. The incredible thing is the fact that Kanye did not do this for publicity and he didn't tell the press about this.
    Joe Arpaio, Controversial Sheriff Pardoned by Trump, Enters Arizona Senate Race

    Joe Arpaio, Controversial Sheriff Pardoned by Trump, Enters Arizona Senate Race

    He faced up to a year in prison, but President Donald Trump pardoned him in a decision that drew scorn from Democrats. Sheriff Joe Arpaio , known for his tough immigration enforcement tactics, said he would run for Sen.
    Link Is Trying To Make Smart Homes Less Annoying

    Link Is Trying To Make Smart Homes Less Annoying

    D-Link teamed up with McAfee and Intel to address these concerns with a powerful, easy to manage, all-in-one solution. To make use of ultra-fast wireless connectivity, D-Link has also announced two new all-weather surveillance cameras.
  • Pubs could stay open until 1am for Harry and Meghan's royal wedding

    Pubs could stay open until 1am for Harry and Meghan's royal wedding

    The pair arrived in the January cold with Meghan wrapped up in a grey woollen coat from Smythe and a Jigsaw scarf. The notes were sent to those who wrote to Kensington Palace following the royal engagement announcement.
    Israel strikes Syrian military base in overnight attacks

    Israel strikes Syrian military base in overnight attacks

    Qutayfeh is in the north-eastern suburbs of Damascus where Syrian Republican Guard units are known to have major outposts. The Israeli military refused to comment, said Reuters.
    France probes Apple over 'deliberate' iPhone throttling

    France probes Apple over 'deliberate' iPhone throttling

    Out of all three countries, planned obsolescence is only a criminal offence in France. The Paris prosecutors has opened an investigation against Apple Inc.
  • Flu cases spike in New Mexico

    Flu cases spike in New Mexico

    If you have a cold, you might have a mild fever and some body aches. "It's been pretty rough the last 2-3 weeks", Chappell said. How can you avoid getting the flu? It looks like this year, the Influenza A component of the vaccine is not that effective.
    Powermat joins WPC, no longer competing with Qi on wireless charging

    Powermat joins WPC, no longer competing with Qi on wireless charging

    Price wise, the iPhone SE 2 is said to cost about $400, which is a tad higher than the current iPhone SE which retails for $349. One of the more recent reports - from late November - claims Apple will release an iPhone SE 2 model in the first half of 2018.
    Altice to Spin off US Unit

    Altice to Spin off US Unit

    Altice N.V. said its Board approved the spin-off of its interest in Altice USA and the renaming of Altice Altice Europe. Altice N.V. formed Altice USA a year ago after purchasing Cablevision Systems Corp. of Bethpage and Suddenlink of St.
  • Peter Beardsley: Newcastle U23s coach takes leave after racism allegations

    Peter Beardsley: Newcastle U23s coach takes leave after racism allegations

    Yasin Ben El-Mhanni joined United a year and a half ago and it is alleged that the bullying started within months of him signing. Newcastle have launched an investigation after an allegation of bullying was made against Under-23s coach Peter Beardsley .
    Goku Black Rose joins Dragon Ball FighterZ & PC Requirements Revealed

    Goku Black Rose joins Dragon Ball FighterZ & PC Requirements Revealed

    The Reddit user also said that Broly and Bardock will be released alongside Broly , Base form Goku, and Base form Vegeta. Leakileaks also mentioned a final form for Android 21 , which confirms that she is the final boss character in the game.
    TCL Reveals 2018 4K Roku Ultra HD TV Lineup with Dolby Vision

    TCL Reveals 2018 4K Roku Ultra HD TV Lineup with Dolby Vision

    Fortunately, that isn't likely the case for TCL's newer TVs, which the company also announced at the press conference. TCL has also announced plans to bring to market the Alto soundbar family in both standard and "smart" solutions.

Most liked

Conte spat with Mourinho is needless
For sure, there is a good opportunity when we play against Manchester United to clarify in a room, me and him. However, Mourinho did not hold back in responses and referred to Conte's match-fixing scandal in 2011.

Pulse Nightclub Shooter's Wife Knew Husband Was Planning Islamist Attack
Her lawyers are arguing that the admission should not be allowed into evidence, saying the agents coerced her into signing it. She faces charges of aiding and abetting by providing material support to a terrorist , and obstruction of justice.

Ultraportable Laptop Powered by Razer Phone
Project Linda , Razer's latest concept, is an ultra-portable laptop that uses Razer's Android-powered phone to operate the device. Connectivity on Project Linda includes a 3.5mm audio jack, USB-A port and a USB-C charging port .

French singer France Gall passes away at 70
Their collaboration and marriage ended abruptly in 1992 when Berger prematurely died of heart attack at 44. It was the first in a long line of hits, all of them penned by Berger, whom Gall married in 1976.

CES 2018: Vivo showcases in-display fingerprint sensor featuring smartphone
As expected, Vivo just unveiled world's first smartphone with in-display fingerprint scanner based on the ultrasonic sensor. A new motion teaser from Vivo hints to a new smartphone with fingerprint scanner mounted under the display.

Mass incarceration book ban lifted at New Jersey prisons
Alexander weighed in on the controversy Monday morning, saying her book had been banned by a number of prisons around the country. A farewell to former governor Brendan Byrne, Gov.

Atkins: Clock ticking on DACA deal
Now, Democrats are trying to protect just the DACA enrollees, while Republicans continue pushing for almost all of their demands. Senate Minority Leader Chuck Schumer of NY blamed the White House, not Senate Republicans, for hampering the immigration talks.

Jennifer Lawrence Blames Emma Stone for Golden Globes No-Show
In fact, numerous beauty looks we saw on the red carpet contained a hidden feminist message that seemed to go largely unnoticed. But things went awry when Stone canceled on her halfway through her "glam", which resulted in an incomplete makeup look .

White House Aide Miller Booted From CNN Tapper Interview
In addition to Miller , White House deputy press secretary Hogan Gidley also told reporters separately that the story was false. About halfway through the interview, things really got heated as Miller continued to dodge Tapper's questions.

Jeff Triplette's horrific night in tweets (with potential happy ending)
Replay showed that Titans running back Derrick Henry was down by contact before the fumble, and the call was reversed upon review. Officials ruled the play dead, however, determining Mariota's forward progress stopped before the ball came loose.

Ibuprofen long-term use linked to infertility in men
The findings by French and Danish researchers followed a six-week clinical study involving 31 men between the ages of 18 and 35. Next, the researchers tested the direct effect of ibuprofen on testicles, using samples that had been taken from organ donors.

Country duo Sugarland to play at Spokane Arena in June
Sugarland's biggest hits include "Baby Girl", "Stay", "Already Gone", "Everyday America" and "Stuck Like Glue". Former One Direction frontman Niall Horan will play the Grandstand on opening night.

Toy maker, VTech, agrees to pay $650K fine
The FTC collaborated with the Office of the Privacy Commissioner of Canada, which is releasing its own Report of Findings . VTech's data security protections and policies will be subject to review every two years for 20 years, per the settlement.

India Considering 7.5% Import Duty On Solar Modules
It alleged the USA of skipping legal steps and failing to follow the procedure while seeking trade sanctions against India. It announced its national solar programme in 2011.

Winter Storm Watch issued for Lincoln/Lancaster County and surrounding area
The heaviest amounts are predicted to fall across south central and eastern Minnesota and northwestern Wisconsin. Blowing snow is also possible, especially across southern Minnesota where blizzard conditions are possible.